Botox vs. Xeomin: What's the difference?

Xeomin, like Botox, is FDA approved for treatment of moderate to severe frown lines and wrinkles.  To better illustrate both their similarities and differences, here are some of the most commonly asked questions we receive from our Denver Botox clientele. 

Botox vs. Xeomin, which is better?


Are Botox and Xeomin the same thing?

Botox vs. Xeomin, they are both botulinum toxin type A, which is synthesized from the bacteria clostridium botulinum.  They work by blocking the release of acetylcholine, the chemical in our bodies that allows nerves and muscles to communicate with each other.  When this is blocked, the muscle receives no signal to contract so it stays in its relaxed state. Over time,  fine lines and wrinkles from repeated facial expressions start to soften and fade. These results only last as long as you’re receiving treatment (usually every 3-4 months) so consistent use is key.


How is Botox and XEOMIN different from each other?

The main difference between the two is their molecular structure.  Botox consists of the neurotoxin (botulinum toxin type A) as well as accessory proteins, and Xeomin is “naked”- just the neurotoxin without the added proteins.

Botox vs Xeomin

BOTOX AND XEOMIN: Which will last longer?

For some patients Botox will last longer than Xeomin, and for other patients the opposite will be true.  There are theories that Botox's accessory proteins is thought to protect the neurotoxin making it last longer, but this has yet to be proven.  There is a legitimate downside to Botox's accessory proteins though-  your body can develop antibodies to them which has the possibility of making Botox less effective over time.


BOTOX AND XEOMIN: Which is best for me?

This question is a little harder to answer, and we usually determine this on a case by case basis.  These are a few questions to ask yourself that can help determine which one may be better for you:

  • Have you had Botox with great results?  Then stick with it!  Why mess with a good thing?

  • Do you feel like your Botox isn’t lasting as long as it used to?  You may want to switch to Xeomin to see if you get longer lasting results.

  • You like Botox but want something more affordable?  Xeomin is $11/unit and is a little less expensive than Botox ($12/unit), which can save you an average of $24-$80 per treatment, depending on the areas to be treated.

Xeomin and Botox are both great for instant gratification and long term correction.


Want to know How to get your Botox to last longer? Read it here.

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